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Cinnamon oil kills mosquitoes more effectively than DEET

Public release date: 16-Jul-2004

American Chemical Society

Cinnamon oil kills mosquitoes
NOTE FOR REPORTERS: The statement in our original news release
(distributed 7-15) that cinnamon oil can "kill mosquito larvae more effectively than
DEET" is misleading since we neglected to point out that DEET is most
commonly used in insect repellants, not as a larvicide. We apologize
for not making this clear. Please disregard the previous version of this news
release and use the following version.
Cinnamon oil shows promise as a great-smelling, environmentally
friendly pesticide, with the ability to kill mosquito larvae, according to a new
study published in the July 14 issue of the Journal of Agricultural and
Food Chemistry, a peer-reviewed journal of the American Chemical Society,
the world�s largest scientific society.

The researchers also expect that cinnamon oil could be a good mosquito
repellant, though they have not yet tested it against adult mosquitoes.

Besides being a summer nuisance, mosquitoes pose some major public
health problems, carrying such deadly agents as malaria, yellow fever and West
Nile virus. While conventional pesticide application is often effective in
controlling mosquito larvae before they hatch, repeated use of these
agents has raised serious environmental and health concerns.

"These problems have highlighted the need for new strategies for
mosquito larval control," says Peter Shang-Tzen Chang, a professor in the School
of Forestry and Resource Conservation at National Taiwan University and
lead author of the paper. Scientists are increasingly turning to more benign
natural chemicals to ward off mosquitoes and other pests.

Chang and his coworkers tested eleven compounds in cinnamon leaf oil
for their ability to kill emerging larvae of the yellow fever mosquito,
Aedes aegypti. "Four compounds � cinnamaldehyde, cinnamyl acetate, eugenol
and anethole � exhibited the strongest activity against A. aegypti in 24
hours of testing," Chang says.

Larvicidal activity is judged with a measurement called LC50. "The LC50
value is the concentration that kills 50 percent of mosquito larvae in
24 hours," Chang explains. Lower LC50 translates into higher activity,
because it takes a lower concentration to kill larvae in the same amount of
time.

All four compounds had LC50 values of less than 50 parts per million
(ppm), with cinnamaldehyde showing the strongest activity at an LC50 of 29
ppm.

Other common essential oils, such as catnip, have shown similar promise
in fighting off mosquitoes, but this is the first time researchers have
demonstrated cinnamon�s potential as a safe and effective pesticide,
according to Chang.

Cinnamaldehyde is the main constituent in cinnamon leaf oil and is used
worldwide as a food additive and flavoring agent. A formulation using
the compound could be sprayed just like a pesticide, but without the
potential for adverse health effects � plus the added bonus of a pleasant smell.

Bark oil from the Cinnamomum cassia tree is the most common source of
cinnamaldehyde, but the tree used in this study � indigenous cinnamon,
or Cinnamomum osmophloeum � has been of interest to researchers because
the constituents of its leaf oil are similar to those of C. cassia bark
oil. The leaves of C. osmophloeum, which grows in Taiwan�s natural hardwood
forests, could be a more economical and sustainable source of cinnamon oil than
isolating it from bark, Chang says.

Though the team only tested the oil against the yellow fever mosquito,
cinnamon oil should prove similarly lethal to the larvae of other
mosquito species, the researchers say. In further studies they plan to test
cinnamon oil against other types of mosquitoes as well as different commercial
pesticides.

"We think that cinnamon oil might also affect adult mosquitoes by
acting as a repellant," Chang says. The researchers haven�t yet tested this
theory, but they plan to find out in the near future.

The Council of Agriculture of the Executive Yuan, a government agency
in Taiwan, provided support for this research.


� Jason Gorss